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Selasa, 28 Desember 2010

[J112.Ebook] Ebook Download Different Worlds Level 2 Elementary/Lower Intermediate Book with Audio CD Pack: Level 2 (Cambridge English Readers: Level 2) (Mixed media p

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Award-winning original fiction for learners of English. At seven levels, from Starter to Advanced, this impressive selection of carefully graded readers offers exciting reading for every student's capabilities.

Published on: 2009
Binding: Misc. Supplies
48 pages

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Sleeping with Dogs is the record of one man's passionate affection for the dog, rooted in his early childhood and lasting undiminished into his dotage. These were for the most part dogs discarded and left to fate - tied to the railings of Kensington Gardens, found with a broken leg in the wilds of Turkey, adopted from an animal rescue home, passed on by the vet - but there was also a whippet of noble pedigree and three generations of a family of crossbreeds in which the whippet strain was strong. They were not pets, but indulged friends and companions, with all of whom he shared his bed, and who richly rewarded him with loyalty and affection. This is not a sentimental or determinedly anthropomorphic book - the dogs remain steadfastly dogs. It is observant and records the canine society of dog and dog as much as the relationship of man and dog. It is, at the same time, a deeply touching account of the lives and very different characters of seventeen dogs over eighty years or so, ranging from Jack Russell to Alsatian through half-boxer, half-pointer and half-Karabas, to purest indecipherable mongrel.

Sales Rank: #1763397 in Books
Published on: 2013-12-02
Original language: English
Number of items: 1
Dimensions: 7.80" h x .70" w x 5.20" l, .60 pounds
Binding: Hardcover
120 pages

About the Author
Addicted to art, Brian Sewell has been the art critic of the London Evening Standard since 1984 - the sad end of a once promising career, the Orwell, Hawthornden and other prizes scant consolation to a man who once enjoyed life as a scholar gypsy.

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5 of 5 people found the following review helpful.
Dog lovers will cry
By Paula M. Gunning
Loved these stories of much loved dogs. The incredible sadness of their passing healed by the next love. Each dog it's own self, each one special and much loved.
You love dogs? You love this book.

0 of 0 people found the following review helpful.
How many of us would lie with a dying dog for days?
By Konrad
Deeply touching to me at times, the depth and sincerity of Brian Sewell's relationships with his dogs over his lifetime is a read not quite like any other I've experienced. I've owned dogs and had to make those decisions for them on ending their lives, but never with the feeling I got reading Sewell writing how he laid on the floor with one of his dying dogs. I've read more about Sewell's life [he died on September 19th 2015] and he was quite a controversial character in his personal and professional life, not one to shy from an intellectual fight or deny a disgraced mentor, he was also a real dog person and his book reflects his lifetime commitment to his animal companions.

Konrad.

0 of 0 people found the following review helpful.
too will love this book
By Just Me
If you are a dog lover, and am I ever!!, you, too will love this book. It's just sweet.

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Minggu, 26 Desember 2010

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Contrary to conventional clinical skill textbooks written in a routine, system based approach, "Clinical Examination: A Problem Based Approach" breaks that mould by presenting clinical cases in a problem solving manner. The book is composed of in-depth dissections of case scenarios and their appropriate investigations. Written by experts from Australia, New Zealand, US and the UK, this book brings an international perspective to a wide variety of specialties including, gastroenterology, neurology, rheumatology, respiratory and the cardiovascular system. Another unique feature of the book is the chapters on examining the older patient, the joints and the vascular system. This publication is a must-have for all medical undergraduates and postgraduates.

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Sales Rank: #4931124 in Books
Brand: Brand: World Scientific Publishing Company
Published on: 2011-03-28
Original language: English
Number of items: 1
Dimensions: 9.10" h x .80" w x 6.10" l, 1.60 pounds
Binding: Hardcover
376 pages

Features

Used Book in Good Condition

From the Inside Flap
Contrary to conventional clinical skill textbooks written in a routine, system based approach, Clinical Examination: A Problem Based Approach breaks that mould by presenting clinical cases in a problem solving manner. The book is composed of in-depth dissections of case scenarios, and their appropriate investigations. Written by experts from Australia, New Zealand, US and the UK, this book brings an international perspective to a wide variety of specialties, including gastroenterology, neurology, rheumatology, respiratory and the cardiovascular system. This publication is a must-have for all medical undergraduates and postgraduates.

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Sabtu, 25 Desember 2010

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Enterprise Risk Management (ERM) represents a fundamental shift in the way businesses must approach risk. As the economy becomes more service driven and globally oriented, businesses cannot afford to let new, unforeseen areas of risk remain unidentified. Currency fluctuations, human resources in foreign countries, evaporating distribution channels, corporate governance, and unprecedented dependence on technology are just a few of the new risks businesses must assess.

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Sales Rank: #2509459 in Books
Published on: 2006-06-05
Original language: English
Number of items: 1
Dimensions: 9.80" h x 1.28" w x 6.91" l, 2.45 pounds
Binding: Hardcover
494 pages

Review
"...provides a thorough introduction to the subject...and places the evolving methodology in context." (Professional Manager, December 2006)

From the Inside Flap
“Enterprise Risk Management is a necessary and valuable tool for identifying, quantifying and mitigating risks across an organisation but it is also a significant undertaking in terms of knowledge and application. In these days of fiscal regulatory and political correctness this book addresses ERM in its broadest sense, providing useful reference and examples. Written in a clear and concise manner the content should be of tremendous value to anyone involved in risk, audit or corporate governance whether as an analyst or board member.”

—Robin Paris,Director, Group Risk, Nestlé

[1 more endorsement to come]

From the Back Cover
The need to understand risks and opportunities is inescapable when striving to grow any business. Hence a business’s ability to prosper in the face of risk is a prime indicator of its ability to compete. However the speed of change in markets, technology and communication combined with the diverse sources of risk, means that for risk management to be effective, it has to be methodical and broad in its approach. Additionally it has to be ingrained in the business psyche, the ‘normal way of doing things’.

Simple Tools and Techniques for Enterprise Risk Management builds from the bottom up to provide a readily understood methodical approach to risk management, while at the same time describing the diverse sources of risk, to encourage a broad approach. To convey the context of enterprise risk management, the commissioning process when engaging consultants, a common approach to implementation and the sources of risk, the book is divided into five parts.

Part 1 describes the catalysts for and developments in corporate governance, internal control and risk management.
Part 2 examines the procurement of risk management services by a client together with the steps a consultant engages in, in terms of interviewing the client prior to an assignment and the preparation of a proposal, to secure a new commission.
Part 3 describes the risk management process being composed of six stages. The inputs, outputs, constraints and enablers of each stage are described to aid implementation.
Part 4 describes what are termed management applications, those sources of risk that to a large extent are under the control of any individual business.
Part 5 describes the external influences on a business which present sources of risk which in the main are beyond the control of any one business

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2 of 4 people found the following review helpful.
Simple Tools and Techniques for Enterprise Risk Management
By Olayinka Ojewole
The Book has explicit information on how ERM could be implemented from a consultant's perspective. The details of various risk areas is also a good reference point for new risk managers.

Thank you.

11 of 29 people found the following review helpful.
A Summary of the Current Techniques
By John Matlock
It is not generally considered that business, all business operates in an element of risk. Everything from the price of supplies to Government actions involve risk. Often this risk is absolutely impossible to predict, i.e. those who went to work at the top of the World Trade Center one September morning. And as a result the analysis of risk in ventures has taken on great urgency.

Commensurate with this has been the development of Enterprise Risk Management (ERM) tools to provide a framework for managing company-wide risk. It begins with overall corporate governance which establishes guidelines for the company to operate. Various phases within the process then include such activities as identifying, evaluating, and controlling risk within those guidelines.

The book is written from a worldwide basis and discusses recent changes in various countries such as the U.K., U.S.A. and Canada. These changes brought about by spectacular busines failures such as Enron, WorldCom, and the resultant troubles of companies such as Arthur Anderson have created an environment where the executive is taking a much greater interest in the management of the company as his risk of prison increases.

Dr. Chapman has a long history of working in the risk management area, including getting his Ph.D. in that area.

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Selasa, 30 November 2010

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Published on: 1707
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Medicinal chemistry is a complex topic. Written in an easy to follow and conversational style, Basic Concepts in Medicinal Chemistry focuses on the fundamental concepts that govern the discipline of medicinal chemistry as well as how and why these concepts are essential to therapeutic decisions. The book emphasizes functional group analysis and the basics of drug structure evaluation.

In a systematic fashion, learn how to identify and evaluate the functional groups that comprise the structure of a drug molecule and their influences on solubility, absorption, acid/base character, binding interactions, and stereochemical orientation. Relevant Phase I and Phase II metabolic transformations are also discussed for each functional group.

Key features include:
• Discussions on the roles and characteristics of organic functional groups, including the identification of acidic and basic functional groups.
• How to solve problems involving pH, pKa, and ionization; salts and solubility; drug binding interactions; stereochemistry; and drug metabolism.
• Numerous examples and expanded discussions for complex concepts.
• Therapeutic examples that link the importance of medicinal chemistry to pharmacy and healthcare practice.
• An overview of structure activity relationships (SARs) and concepts that govern drug design.
• Review questions and practice problems at the end of each chapter that allow readers to test their understanding, with the answers provided in an appendix.

Whether you are just starting your education toward a career in a healthcare field or need to brush up on your organic chemistry concepts, this book is here to help you navigate medicinal chemistry.

About the Authors

Marc W. Harrold, BS, Pharm, PhD, is Professor of Medicinal Chemistry at the Mylan School of Pharmacy, Duquesne University, Pittsburgh, PA. Professor Harrold is the 2011 winner of the Omicron Delta Kappa "Teacher of the Year" award at Duquesne University. He is also the two-time winner of the "TOPS" (Teacher of the Pharmacy School) award at the Mylan School of Pharmacy.

Robin M. Zavod, PhD, is Associate Professor for Pharmaceutical Sciences at the Chicago College of Pharmacy, Midwestern University, Downers Grove, IL, where she was awarded the 2012 Outstanding Faculty of the Year award. Professor Zavod also serves on the adjunct faculty for Elmhurst College and the Illinois Institute of Technology. She currently serves as Editor-in-Chief of the journal Currents in Pharmacy Teaching and Learning.

Sales Rank: #348305 in Books
Brand: Brand: American Society of Health-System Pharmacists
Published on: 2013-01-31
Original language: English
Number of items: 1
Dimensions: 9.90" h x .90" w x 7.00" l, 1.80 pounds
Binding: Paperback
460 pages

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Used Book in Good Condition

Review

Basic Concepts of Medicinal Chemistry

By Marc W. Harrold and Robin M. Zavod

Pharmaceutical Journal, Volume 290, Page 343, March 23, 2013

Reviewer: Laurence A Goldberg is a pharmaceutical consultant from Bury, Lancashire

All you need to know about medicinal chemistry.

This book focuses solely on the basic, fundamental concepts governing the discipline of medicinal chemistry. Every drug is a chemical structure that contains numerous functional groups arranged in a specific manner. These functional groups determine the interactions of the drug molecule with its biological target, its pharmacological action, the route by which it is administered, the extent to which it is metabolized and the presence or absence of specific adverse reactions or drug interactions.

The chapters in this book have been carefully organized to allow the reader to gain knowledge progressively about the chemistry of drug molecules, with each chapter building on the previous one. The first chapter reviews the numbering of alicyclic and heterocyclic rings, the designation of aromatic ring positions and steroid nomenclature, while the second chapter focuses on the chemical characteristics of functional groups and the roles they play in drug action.

The following chapters identify those functional groups that are acidic or basic, review a strategy to calculate the extent to which they are ionised in a given environment and then examine how these characteristics contribute to the overall solubility of the drug molecule. Subsequent chapters discuss the types of binding interactions that can occur between a drug molecule and its biological target and how stereochemistry of the molecule can also affect its interaction with biological targets. Emphasis is placed on the pharmacological and therapeutic differences that can occur between enantiomers.

A chapter is devoted to exploring the metabolism of drug molecules by various enzymes. It identifies the functional groups that are susceptible to each type of metabolic transformation, enabling the reader to become more proficient in predicting the possible metabolic transformations for a given drug molecule. In the final chapter, the concept of structure-activity relationships is introduced along with the concepts of molecular modification to design new drugs and analogues of existing drugs. This book is extremely well structured and easy to follow. It navigates through medicinal chemistry in a way that makes the subject easy to understand. It will be a great asset to students embarking upon a healthcare career or to practitioners who need to brush up on medicinal chemistry.

(Laurence A. Goldberg Pharmaceutical Journal 2013-03-23)

null (Thomas L. Lemke, PhD Pharmacy Teaching and Learning 2013-04-04)

About the Author

Marc W. Harrold, BS, Pharm, PhD, is Professor of Medicinal Chemistry at the Mylan School of Pharmacy, Duquesne University, Pittsburgh, PA. Professor Harrold is the 2011 winner of the Omicron Delta Kappa "Teacher of the Year" award at Duquesne University. He is also a multi-year recipient of the "TOPS" (Teacher of the Pharmacy School) award at the Mylan School of Pharmacy.

Robin M. Zavod, PhD, is Associate Professor for Pharmaceutical Sciences at the Chicago College of Pharmacy, Midwestern University, Downers Grove, IL, where she was awarded the 2012 Outstanding Faculty of the Year award. Professor Zavod also serves on the adjunct faculty for Elmhurst College and the Illinois Institute of Technology. She currently serves as Editor-in-Chief of the journal Currents in Pharmacy Teaching and Learning.

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7 of 7 people found the following review helpful.
Medicinal Chemistry makes sense
By SydneyDAK
This book makes Medicinal Chemistry make sense. It's laid out in easy to digest chapters with lots of examples and practice problems. Other books I've read on the subject aren't written for someone with not a lot of background in Chemistry, so they were difficult and muddy. Harrold and Zavod did a great job providing a breakdown of the fundamental pieces of Medicinal Chemistry. I honestly enjoyed reading this book and understand so much more of the foundational pieces I need for my continuing years in Pharmacy School. I would highly recommend everyone that's looking for a place to start or to solidify their skills to read this book. It's the one book I will definitely use over again.

1 of 1 people found the following review helpful.
Decent Read
By jleudy
I think the book makes medicinal chemistry overview as interesting as it can be. It is surprisingly comprehensive because it is only roughly 480 pages long. Overall decent read if you need to brush up on chemistry basics.

1 of 1 people found the following review helpful.
it explains the basic concepts in a simple in which you will digest the the subject very easily.
By Mansour S. M. Turki
Honestly, this book is an essential book for a person studying drug discovery and drug development courses. It also explains the basic concepts in a simple way, which makes you digest the subject very easily.

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Sales Rank: #5665866 in Books
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Binding: Unknown Binding

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